Being Full Doesn’t Stop at
the Gut — It Involves
the Brain Too
This connection, known as the Gut-Brain Axis, relies on mechanical and chemical signals, such as GLP-1, to regulate food intake and promote satiety (the feeling of fullness)1.
1 Mayer, E. A. (2011). Gut feelings: the emerging biology of gut–brain communication. Nature Reviews Neuroscience, 12(8), 453–466.
Satiety Can’t be Measured in Calories
Calories measure the amount of energy you get from food, but more calories do not translate to higher satiety. Research actually suggests the opposite – the higher the caloric density (calories/gram), the less satiating2.
Satiety Index vs
Caloric Density of Various Foods — Fig. 12
2Holt, S. H., Miller, J. C., Petocz, P., & Farmakalidis, E. (1995). A satiety index of common foods. European journal of clinical nutrition, 49(9), 675–690.
Satiety Index vs
Caloric Density of Various Foods — Fig. 12
The Body was Designed to Feel Full
Satiety is a natural human pathway in the Gut-Brain Axis that helps regulate food intake, but different foods impact satiety in unique ways. Take a beet sugar (sucrose) and a beet fiber (fructooglisaccharides or FOS) - both are carbohydrates from the same plant, but due to their different molecular structures, they are metabolized by distinct pathways in the body. Beet sugar is rapidly absorbed in the small intestines, while beet FOS resists digestion and is fermented in the colon – delivering fewer calories, more slowly3.
When eating the full beet, these two carbohydrates, along with a variety of other phytonutrients, activate a series of receptors across the digestive system, leading to a robust satiety response relative to calories consumed. However, when sugar is refined out of the beet and eaten separately, you are left with only a part of the satiety equation with some of the receptors understimulated.
Time to Peak Absorption — Fig. 23
Beet FOS has half the calories and takes ~6x longer to absorb than beet sugar
3van Trijp, M. P. H., Rios-Morales, M., Witteman, B., Abegaz, F., Gerding, A., An, R., Koehorst, M., Evers, B., van Dongen, K. C. V., Zoetendal, E. G., Schols, H., Afman, L. A., Reijngoud, D. J., Bakker, B. M., & Hooiveld, G. J. (2024). Intraintestinal fermentation of fructo- and galacto-oligosaccharides and the fate of short-chain fatty acids in humans. iScience, 27(3), 109208.
Time to Peak Absorption — Fig. 23
Today’s Diet is Optimized for Taste, not Satiety
Many foods in the modern diet are calorically dense with high fat and/or refined carbohydrates4. Studies have shown these foods can stimulate the reward pathways in the Gut Brain Axis, keeping you craving more5. Because some of the most satiating components have been lost in processing, you are left eating more than you need and feeling less full than you should.
Comparison of Caloric Profiles — Fig. 3
Fig. 3 — National brand classic potato chips, cracker, and chewy chocolate chip granola bar nutrition compared to VORA™ ingredients as of 2025.
4 Drewnowski A. (1998). Energy density, palatability, and satiety: implications for weight control. Nutrition reviews, 56(12), 347–353.
5 Edwin Thanarajah, S., DiFeliceantonio, A. G., Albus, K., Kuzmanovic, B., Rigoux, L., Iglesias, S., Hanßen, R., Schlamann, M., Cornely, O. A., Brüning, J. C., Tittgemeyer, M., & Small, D. M. (2023). Habitual daily intake of a sweet and fatty snack modulates reward processing in humans. Cell metabolism, 35(4), 571–584.e6
Comparison of Caloric Profiles — Fig. 3
Comparison of Caloric Profiles — Fig. 3
Comparison of Caloric Profiles — Fig. 3
Experience VORA™ To The Fullest
The VORA™ Origin Satiety Complex
Because today’s diet doesn’t keep you full, we created VORA™.
Emerging science suggests that certain elements lost in refined foods, such as fiber and other plant-derived phytonutrients, can activate satiety pathways under-stimulated by the modern diet6.
VORA™ developed the ORIGIN Satiety Complex to deliver a curated and concentrated blend of these ingredients, keeping you fuller longer.
Oat Beta Glucan
Spinach Extract
Wheat Fiber Extract
Resistant Potato Starch (Solnul®)
6Tsuda T. (2015). Possible abilities of dietary factors to prevent and treat diabetes via the stimulation of glucagon-like peptide-1 secretion. Molecular nutrition & food research, 59(7), 1264–1273.
Life Is Better Full
VORA™ is pioneering satiety solutions that help you feel
full in less than 50 calories, satisfaction guaranteed.
Life Is Better Full
VORA™ is pioneering satiety solutions that help you feel
full in less than 50 calories, satisfaction guaranteed.
ORIGIN Satiety Complex